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10 Causes of Nephrotic Syndrome

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Minimal Change Disease (MCD): This is the most common cause of nephrotic syndrome in children.

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Focal Segmental Glomerulosclerosis (FSGS): FSGS causes scarring (sclerosis) in specific segments of the kidney's glomeruli, leading to protein leakage into the urine.

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Membranous Nephropathy: In this condition, the glomerular basement membrane becomes thickened, leading to protein leakage.

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Diabetic Nephropathy: High blood sugar levels associated with diabetes can damage the kidneys over time, leading to nephrotic syndrome.

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Systemic Lupus Erythematosus (SLE): Lupus nephritis, a complication of systemic lupus erythematosus, can cause inflammation in the kidneys, leading to nephrotic syndrome.

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Amyloidosis: In this condition, abnormal proteins called amyloids build up in the kidneys, impairing their function and causing nephrotic syndrome.

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Membranoproliferative Glomerulonephritis (MPGN): MPGN is a type of kidney inflammation that affects the glomeruli and can lead to nephrotic syndrome.

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IgA Nephropathy (Berger's Disease): This condition occurs when immunoglobulin A (IgA) deposits in the glomeruli, leading to inflammation and kidney damage.

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Infections: Certain infections, such as HIV, hepatitis B and C, and malaria, can cause nephrotic syndrome by damaging the kidneys.