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8 Causes of Bone Cancer

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Genetic Factors: Inherited genetic mutations, such as in conditions like Li-Fraumeni syndrome and hereditary retinoblastoma, can increase the risk

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Radiation Exposure: Previous exposure to high doses of radiation, either from radiation therapy for previous cancers or from environmental sources, can increase the risk

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Paget's Disease: Paget's disease of bone, a condition characterized by abnormal bone remodeling, can sometimes lead to the development of bone cancer

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Bone Marrow Transplant: Individuals who have undergone bone marrow transplantation may have an increased risk of developing bone cancer

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Chemical Exposure: Prolonged exposure to certain chemicals, such as those used in the rubber industry, may increase the risk of bone cancer

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Growth Factors: Certain growth factors and hormones, such as insulin-like growth factor 1 (IGF-1), have been associated with an increased risk of bone cancer

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Age: While bone cancer can occur at any age, it is more commonly diagnosed in older adults and adolescents

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Previous Bone Conditions: Certain benign bone conditions, such as benign bone tumors or chronic osteomyelitis (bone infection), may increase the risk of developing bone cancer